3cke A 2.4 BS01 FDF A 1 Y67 F87 D90 F153 L184 N219 W308 R314 Y315 Y55 F75 D78 F141 L172 N207 W286 R292 Y293 Y67 F87 F153 K181 W308 Y55 F75 F141 K169 W286 4.2.3.9 0016829,0045483,0046872 -logKd/Ki=6.10, Ki=0.8uM Q9UR08 18385128 400 SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTLCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV 3cke B 2.4 BS01 FDF B 1 F87 D90 F153 R314 F75 D78 F141 R294 Y67 F87 F153 K181 W308 Y55 F75 F141 K169 W288 4.2.3.9 0016829,0045483,0046872 Q9UR08 18385128 401 SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTSILCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV 3cke C 2.4 BS01 FDF C 1 F87 D90 F153 L184 N219 R314 Y315 F75 D78 F141 L172 N207 R292 Y293 Y67 F87 F153 K181 W308 Y55 F75 F141 K169 W286 4.2.3.9 0016829,0045483,0046872 Q9UR08 18385128 402 SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTLCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV 3cke D 2.4 BS01 MG D 1 N219 S223 E227 N197 S201 E205 Y67 F87 F153 K181 W308 Y49 F69 F132 K159 W275 4.2.3.9 0016829,0045483,0046872 Q9UR08 18385128 701 SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWKARKKVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRRPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYLCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV 3cke D 2.4 BS02 POP D 1 N219 E227 Y315 N197 E205 Y282 Y67 F87 F153 K181 W308 Y49 F69 F132 K159 W275 4.2.3.9 0016829,0045483,0046872 Q9UR08 18385128 5963 SLEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWKARKKVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRRPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYLCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV