3c84 A 1.94 BS01 TH4 A 1 W147 Y188 C190 Y195 W150 Y191 C193 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM -logKd/Ki=7.85, Kd=14nM Ki=3.9nM Q8WSF8 18477694 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 3c84 A 1.94 BS02 TH4 B 1 Y55 M116 I118 Y58 M119 I121 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM -logKd/Ki=7.85, Kd=14nM Ki=3.9nM Q8WSF8 18477694 302 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 3c84 B 1.94 BS01 TH4 B 1 W147 Y188 C190 Y195 W149 Y190 C192 Y197 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM Ki=3.9nM Q8WSF8 18477694 302 DDKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 3c84 B 1.94 BS02 TH4 C 1 Y55 M116 I118 Y57 M118 I120 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM Ki=3.9nM Q8WSF8 18477694 303 DDKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 3c84 C 1.94 BS01 TH4 C 1 W147 Y188 C190 Y195 W148 Y189 C191 Y196 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM Ki=3.9nM Q8WSF8 18477694 303 DKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 3c84 C 1.94 BS02 TH4 D 1 Y55 M116 I118 Y56 M117 I119 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM Ki=3.9nM Q8WSF8 18477694 304 DKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 3c84 D 1.94 BS01 TH4 D 1 W147 Y188 C190 Y195 W148 Y189 C191 Y196 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=14nM Ki=3.9nM Q8WSF8 18477694 304 KLHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 3c84 E 1.94 BS01 TH4 A 1 Y55 M116 I118 Y53 M114 I116 ? 0004888,0005216,0005230,0006811,0016020,0034220 -logKd/Ki=7.85, Kd=14nM Ki=3.9nM Q8WSF8 18477694 301 DKLHSQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER