3bur A 1.62 BS01 NAP A 1 G24 T25 Y26 D53 Y58 N170 Q193 Y219 S220 P221 L222 T224 S225 I271 P272 K273 S274 R279 E282 N283 G23 T24 Y25 D52 Y57 N169 Q192 Y218 S219 P220 L221 T223 S224 I270 P271 K272 S273 R278 E281 N282 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 P51857 18407998 328 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 3bur A 1.62 BS02 TES A 1 Y26 W89 Y132 S225 N227 W230 V309 Y25 W88 Y131 S224 N226 W229 V308 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 Ki=14.45uM P51857 18407998 339 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 3bur B 1.62 BS01 NAP B 1 G24 T25 Y26 D53 Y58 N170 Q193 Y219 S220 P221 L222 T224 S225 L239 I271 P272 K273 S274 R279 E282 N283 G23 T24 Y25 D52 Y57 N169 Q192 Y218 S219 P220 L221 T223 S224 L238 I270 P271 K272 S273 R278 E281 N282 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 P51857 18407998 327 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 3bur B 1.62 BS02 TES B 1 Y26 W89 Y132 S225 W230 V231 V309 Y25 W88 Y131 S224 W229 V230 V308 D53 Y58 K87 E120 D52 Y57 K86 E119 1.3.1.3 0004032,0004033,0005496,0005515,0005737,0005829,0006699,0006707,0007586,0008202,0008207,0008209,0016042,0016229,0016491,0030573,0047086,0047787 Ki=14.45uM P51857 18407998 340 DLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY