3bpr A 2.8 BS01 OLP A 1 A617 F673 M674 K675 G677 D678 M730 A43 F88 M89 K90 G92 D93 M145 D723 A725 R727 N728 D741 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=4.95, IC50=11.3uM Q12866 19028587 900 NKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPD 3bpr B 2.8 BS01 OLP B 1 V601 A617 F673 M674 K675 G677 M730 V25 A41 F83 M84 K85 G87 M140 D723 A725 R727 N728 D741 D133 A135 R137 N138 D151 2.7.10.1 0004672,0004713,0005524,0006468 Q12866 19028587 900 KLEDVVIDRNLLILGKILGEEFGSVMEGNLKQEDGTSLKVAVKTMKLIEEFLSEAACMKDFSHPNVIRLLGVCIEMPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPD 3bpr C 2.8 BS01 OLP C 1 V601 A617 F673 M674 K675 G677 D678 M730 V27 A43 F86 M87 K88 G90 D91 M143 D723 A725 R727 N728 D741 D136 A138 R140 N141 D154 2.7.10.1 0004672,0004713,0005524,0006468 Q12866 19028587 900 NKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKIEEFLSEAACMKDFSHPNVIRLLGVCIEMSQPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPD 3bpr D 2.8 BS01 OLP D 1 V601 A617 F673 M674 K675 G677 D678 M730 V27 A43 F86 M87 K88 G90 D91 M143 D723 A725 R727 N728 D741 D136 A138 R140 N141 D154 2.7.10.1 0004672,0004713,0005524,0006468 Q12866 19028587 900 NKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPD