3bgz A 2.4 BS01 VX3 A 1 L44 G45 F49 V52 K67 I104 I185 D186 L12 G13 F17 V20 K35 I67 I148 D149 D167 K169 N172 D186 L193 T204 D130 K132 N135 D149 L156 T167 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 Ki=0.55uM -logKd/Ki=6.26, Ki=0.55uM IC50=550nM, Ki=550nM P11309 18290603 314 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGERVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH