3axk A 1.9 BS01 MG A 1 K201 D203 E204 K178 D180 E181 K175 K201 D202 D203 E204 H294 H327 K152 K178 D179 D180 E181 H271 H304 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 P0C512 22609438 478 YKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIW 3axk A 1.9 BS02 NDP A 1 K175 R295 H298 S379 G380 G381 G404 K152 R272 H275 S351 G352 G353 G376 K175 K201 D202 D203 E204 H294 H327 K152 K178 D179 D180 E181 H271 H304 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 Ki=70uM P0C512 22609438 479 YKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIW 3axk A 1.9 BS03 NDP A 2 E60 T68 N123 G126 F127 E41 T45 N100 G103 F104 K175 K201 D202 D203 E204 H294 H327 K152 K178 D179 D180 E181 H271 H304 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 Ki=70uM P0C512 22609438 480 YKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIW 3axk B 1.9 BS01 NDP A 1 E60 N123 G126 F127 E40 N97 G100 F101 D203 E204 H294 H327 D177 E178 H268 H301 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 P0C512 22609438 479 KLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWK 3axk B 1.9 BS02 NDP A 2 K175 R295 H298 S379 G380 G381 G404 K149 R269 H272 S346 G347 G348 G371 D203 E204 H294 H327 D177 E178 H268 H301 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 P0C512 22609438 480 KLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWK 3axk B 1.9 BS03 MG B 1 K201 D203 E204 K175 D177 E178 D203 E204 H294 H327 D177 E178 H268 H301 4.1.1.39 0000166,0000287,0004497,0009507,0009536,0009853,0015977,0015979,0016829,0016984,0019253,0046872 P0C512 22609438 478 KLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWK