2zoq A 2.39 BS01 5ID A 1 I48 E50 V56 A69 Q122 M125 S170 L173 I25 E27 V33 A46 Q99 M102 S147 L150 D166 K168 S170 N171 D184 T207 D143 K145 S147 N148 D161 T184 2.7.11.24 0000165,0001784,0004672,0004674,0004707,0005515,0005524,0005634,0005635,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005829,0005856,0005886,0005901,0005925,0006351,0006468,0006915,0006974,0008286,0009887,0010759,0014032,0014044,0016020,0016310,0019233,0019902,0030278,0030509,0030641,0030878,0031143,0031281,0031663,0032206,0032496,0032872,0033554,0034198,0035556,0038083,0038133,0042473,0042552,0042770,0042802,0043330,0045944,0048009,0048538,0050804,0051090,0051216,0051403,0051493,0060020,0060324,0060425,0060440,0061308,0070161,0070371,0070374,0070498,0070849,0071260,0071356,0072584,0090170,0098792,0098978,0106310,0120041,0140297,1904262,1904417,2000641 ic50=0.9uM -logKd/Ki=6.05, IC50=0.9uM P27361 18983981 382 VPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGV 2zoq B 2.39 BS01 5ID B 1 I48 V56 A69 Q122 D123 M125 S170 L173 I25 V33 A46 Q99 D100 M102 S147 L150 D166 K168 S170 N171 D184 T207 D143 K145 S147 N148 D161 T184 2.7.11.24 0000165,0001784,0004672,0004674,0004707,0005515,0005524,0005634,0005635,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005829,0005856,0005886,0005901,0005925,0006351,0006468,0006915,0006974,0008286,0009887,0010759,0014032,0014044,0016020,0016310,0019233,0019902,0030278,0030509,0030641,0030878,0031143,0031281,0031663,0032206,0032496,0032872,0033554,0034198,0035556,0038083,0038133,0042473,0042552,0042770,0042802,0043330,0045944,0048009,0048538,0050804,0051090,0051216,0051403,0051493,0060020,0060324,0060425,0060440,0061308,0070161,0070371,0070374,0070498,0070849,0071260,0071356,0072584,0090170,0098792,0098978,0106310,0120041,0140297,1904262,1904417,2000641 ic50=0.9uM P27361 18983981 382 VPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGV