2zm3 A 2.5 BS01 575 A 1 L1005 Q1007 V1013 A1031 M1079 L1081 M1082 T1083 G1085 M1142 L26 Q28 V34 A52 M100 L102 M103 T104 G106 M160 D1135 R1139 N1140 D1153 E1162 D153 R157 N158 D171 E180 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Kd=0.614uM -logKd/Ki=6.21, Kd=0.614uM IC50=2420nM P08069 18501599 1 SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPENPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN 2zm3 B 2.5 BS01 575 B 1 L1005 V1013 A1031 M1079 L1081 M1082 G1085 M1142 L26 V34 A52 M100 L102 M103 G106 M156 D1135 R1139 N1140 D1153 E1162 D149 R153 N154 D167 E176 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Kd=0.614uM IC50=2420nM P08069 18501599 1 SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN 2zm3 C 2.5 BS01 575 C 1 L1005 V1013 A1031 M1079 L1081 M1082 T1083 G1085 M1142 L26 V34 A52 M100 L102 M103 T104 G106 M156 D1135 R1139 N1140 D1153 E1162 D149 R153 N154 D167 E176 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Kd=0.614uM IC50=2420nM P08069 18501599 1 SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN 2zm3 D 2.5 BS01 575 D 1 L1005 Q1007 V1013 A1031 L1081 M1082 T1083 G1085 M1142 L26 Q28 V34 A52 L102 M103 T104 G106 M153 D1135 R1139 N1140 D1153 E1162 D146 R150 N151 D164 E173 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Kd=0.614uM IC50=2420nM P08069 18501599 1 SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN