2ydj A 1.85 BS01 YDJ A 1 L15 Y20 A36 E85 Y86 C87 E134 N135 L137 D148 L8 Y13 A29 E70 Y71 C72 E119 N120 L122 D133 D130 K132 E134 N135 D148 T170 D115 K117 E119 N120 D133 T155 2.7.11.1 0000077,0004672,0004674,0005524,0006468 ic50=0.005uM -logKd/Ki=8.30, IC50=5nM IC50=6.0nM, EC50=10nM O14757 22551018 1270 DWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMNIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPL 2ydj B 1.85 BS01 YDJ B 1 L15 Y20 A36 E85 Y86 C87 G90 E134 N135 L137 D148 L7 Y12 A28 E69 Y70 C71 G74 E118 N119 L121 D132 D130 K132 E134 N135 D148 T170 D114 K116 E118 N119 D132 T154 2.7.11.1 0000077,0004672,0004674,0005524,0006468 ic50=0.005uM IC50=6.0nM, EC50=10nM O14757 22551018 1270 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMNIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPL