2y80 A 1.9 BS01 439 A 1 E97 T98 Y99 F174 D189 A190 Q192 V213 W215 G216 G219 C220 G226 I227 Y228 E83 T84 Y85 F162 D179 A180 Q182 V203 W205 G206 G208 C209 G216 I217 Y218 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 Ki=9nM -logKd/Ki=8.05, Ki=9nM Ki=3nM P00742 21349710 1245 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 2y80 A 1.9 BS02 CA A 1 D70 N72 Q75 E80 D56 N58 Q61 E66 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 P00742 21349710 1246 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 2y80 A 1.9 BS03 MG A 1 Y185 D185A R222 K224 Y173 D174 R211 K214 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 P00742 21349710 1247 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 2y80 B 1.9 BS01 439 A 1 T48 L49 T51 L52 3.4.21.6 0005509,0005576 Ki=3nM P00742 21349710 1245 RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL