2wk6 A 2.5 BS01 IUR A 1 H116 T118 L148 Y199 R202 I214 S217 I218 K221 H82 T84 L114 Y165 R168 I180 S183 I184 K187 D114 K115 H116 S117 T154 D195 R202 S217 K221 K222 D80 K81 H82 S83 T120 D161 R168 S183 K187 K188 2.4.2.4 0000002,0001525,0004645,0005515,0005829,0006206,0006213,0006935,0007165,0008083,0009032,0016154,0016757,0016763,0030154,0031641,0042803,0046074,0051969,1905333 Ki=0.48mM -logKd/Ki=3.32, Ki=0.48mM P19971 19555658 1482 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPP 2wk6 B 2.5 BS01 IUR A 1 P479 P480 P445 P446 D114 K115 H116 S117 T154 D195 R202 S217 K221 K222 D80 K81 H82 S83 T120 D161 R168 S183 K187 K188 2.4.2.4 0000002,0001525,0004645,0005515,0005829,0006206,0006213,0006935,0007165,0008083,0009032,0016154,0016757,0016763,0030154,0031641,0042803,0046074,0051969,1905333 Ki=0.48mM P19971 19555658 1482 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPP 2wk6 B 2.5 BS02 IUR B 1 H116 T118 L148 Y199 R202 I214 S217 I218 K221 H82 T84 L114 Y165 R168 I180 S183 I184 K187 D114 K115 H116 S117 T154 D195 R202 S217 K221 K222 D80 K81 H82 S83 T120 D161 R168 S183 K187 K188 2.4.2.4 0000002,0001525,0004645,0005515,0005829,0006206,0006213,0006935,0007165,0008083,0009032,0016154,0016757,0016763,0030154,0031641,0042803,0046074,0051969,1905333 Ki=0.48mM P19971 19555658 1482 QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPP