2wd1 A 2.0 BS01 ZZY A 1 I1084 V1092 A1108 L1157 Y1159 M1160 M1211 A1221 D1222 Y1230 I30 V38 A54 L100 Y102 M103 M154 A164 D165 Y173 D1204 A1206 R1208 N1209 D1222 A1243 D147 A149 R151 N152 D165 A186 2.7.10.1 0004672,0004713,0005524,0006468 ic50=82nM -logKd/Ki=7.09, IC50=82nM IC50=82nM P08581 19369077 2347 LSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG 2wd1 A 2.0 BS02 GBL A 1 L1140 L1157 F1223 L1225 A1226 L86 L100 F166 L168 A169 D1204 A1206 R1208 N1209 D1222 A1243 D147 A149 R151 N152 D165 A186 2.7.10.1 0004672,0004713,0005524,0006468 P08581 19369077 2348 LSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG 2wd1 A 2.0 BS03 GBL A 2 F1089 R1227 D1228 M1229 Y1235 K1244 F35 R170 D171 M172 Y178 K187 D1204 A1206 R1208 N1209 D1222 A1243 D147 A149 R151 N152 D165 A186 2.7.10.1 0004672,0004713,0005524,0006468 P08581 19369077 2349 LSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG