2vzm A 1.85 BS01 HEM A 1 M92 L93 H100 R104 A243 G244 T247 T248 L251 T294 R296 A346 F347 H352 C354 I355 G356 A360 M81 L82 H89 R93 A232 G233 T236 T237 L240 T283 R285 A335 F336 H341 C343 I344 G345 A349 D23 P47 F180 A243 E246 T247 T248 V290 C354 I355 G356 E363 I395 D12 P36 F169 A232 E235 T236 T237 V279 C343 I344 G345 E352 I384 1.14.15.33 0004497,0005506,0016705,0017000,0020037,0033068,0046872,0055114 O87605 19124459 1407 PPVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWR 2vzm A 1.85 BS02 NRB A 1 F178 M191 I239 T247 I395 F167 M180 I228 T236 I384 D23 P47 F180 A243 E246 T247 T248 V290 C354 I355 G356 E363 I395 D12 P36 F169 A232 E235 T236 T237 V279 C343 I344 G345 E352 I384 1.14.15.33 0004497,0005506,0016705,0017000,0020037,0033068,0046872,0055114 Kd=171.9uM O87605 19124459 1408 PPVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWR 2vzm B 1.85 BS01 HEM B 1 M92 L93 H100 R104 L240 A243 G244 T247 T248 L251 T294 R296 A346 F347 H352 C354 I355 G356 A360 M80 L81 H88 R92 L228 A231 G232 T235 T236 L239 T282 R284 A334 F335 H340 C342 I343 G344 A348 D23 P47 F180 A243 E246 T247 T248 V290 C354 I355 G356 E363 I395 D11 P35 F168 A231 E234 T235 T236 V278 C342 I343 G344 E351 I383 1.14.15.33 0004497,0005506,0016705,0017000,0020037,0033068,0046872,0055114 O87605 19124459 1407 PVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWR 2vzm B 1.85 BS02 NRB B 1 E85 L93 E94 F178 H238 I239 V242 A243 M394 I395 E73 L81 E82 F166 H226 I227 V230 A231 M382 I383 D23 P47 F180 A243 E246 T247 T248 V290 C354 I355 G356 E363 I395 D11 P35 F168 A231 E234 T235 T236 V278 C342 I343 G344 E351 I383 1.14.15.33 0004497,0005506,0016705,0017000,0020037,0033068,0046872,0055114 Kd=171.9uM O87605 19124459 1408 PVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWR