2vvt A 1.65 BS01 I24 A 1 V14 V152 E153 N155 H187 L190 I250 W254 V20 V158 E159 N161 H193 L196 I251 W255 D11 S12 C74 E153 C185 H187 D17 S18 C80 E159 C191 H193 5.1.1.3 0008360,0008881,0009252,0016853,0016855,0036361,0042802,0071555 ic50=5.8uM -logKd/Ki=5.24, IC50=5.8uM IC50=5800nM Q836J0 18614367 1269 VPRGSHMSNQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVALEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPAIEVTSLACPKFVPIVESNQYRSSVAKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPPHEFYTTGSAKMFEEIASSWLGIENLKAQQIHLG 2vvt A 1.65 BS02 DGL A 1 S12 P42 Y43 G44 C74 N75 T76 C185 T186 H187 S18 P48 Y49 G50 C80 N81 T82 C191 T192 H193 D11 S12 C74 E153 C185 H187 D17 S18 C80 E159 C191 H193 5.1.1.3 0008360,0008881,0009252,0016853,0016855,0036361,0042802,0071555 Q836J0 18614367 1270 VPRGSHMSNQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVALEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPAIEVTSLACPKFVPIVESNQYRSSVAKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPPHEFYTTGSAKMFEEIASSWLGIENLKAQQIHLG 2vvt B 1.65 BS01 I24 B 1 V152 E153 N155 E249 I250 W254 V150 E151 N153 E247 I248 W252 D11 S12 C74 E153 C185 H187 D9 S10 C72 E151 C183 H185 5.1.1.3 0008360,0008881,0009252,0016853,0016855,0036361,0042802,0071555 ic50=5.8uM IC50=5800nM Q836J0 18614367 1269 NQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVALEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPAIEVTSLACPKFVPIVESNQYRSSVAKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPEAPTQPHEFYTTGSAKMFEEIASSWLGIENLKAQQIHLG 2vvt B 1.65 BS02 DGL B 1 S12 P42 Y43 G44 C74 N75 T76 C185 T186 H187 S10 P40 Y41 G42 C72 N73 T74 C183 T184 H185 D11 S12 C74 E153 C185 H187 D9 S10 C72 E151 C183 H185 5.1.1.3 0008360,0008881,0009252,0016853,0016855,0036361,0042802,0071555 Q836J0 18614367 1270 NQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVALEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPAIEVTSLACPKFVPIVESNQYRSSVAKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPEAPTQPHEFYTTGSAKMFEEIASSWLGIENLKAQQIHLG