2vew A 2.0 BS01 IZ3 A 1 Y46 D48 V49 D181 F182 C215 S216 A217 I219 G220 R221 D298 Y44 D46 V47 D179 F180 C213 S214 A215 I217 G218 R219 D296 D181 C215 R221 S222 Q262 D179 C213 R219 S220 Q260 3.1.3.48 0004725,0006470,0016311 ic50=64nM -logKd/Ki=7.19, IC50=64nM P18031 18037290 1299 MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED