2vd1 A 2.25 BS01 GSH A 1 Y8 R14 W39 K43 K50 I51 Q63 S64 Y7 R13 W38 K42 K49 I50 Q62 S63 Y8 R14 R19 W104 Y7 R13 R18 W103 2.5.1.18,5.3.99.2 0000287,0001516,0004364,0004667,0005509,0005515,0005654,0005737,0005829,0006693,0007165,0007626,0009624,0010269,0016740,0016853,0042803,0043231,0046872,2000255 O60760 18341273 1200 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 2vd1 B 2.25 BS01 D28 B 1 M11 G13 R14 Q36 M99 W104 Y152 L199 M10 G12 R13 Q35 M98 W103 Y151 L198 Y8 R14 R19 W104 Y7 R13 R18 W103 2.5.1.18,5.3.99.2 0000287,0001516,0004364,0004667,0005509,0005515,0005654,0005737,0005829,0006693,0007165,0007626,0009624,0010269,0016740,0016853,0042803,0043231,0046872,2000255 ic50=0.138uM -logKd/Ki=6.86, IC50=0.138uM IC50=94600nM O60760 18341273 1200 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 2vd1 B 2.25 BS02 GSH B 1 Y8 R14 W39 K43 K50 I51 Q63 S64 Y7 R13 W38 K42 K49 I50 Q62 S63 Y8 R14 R19 W104 Y7 R13 R18 W103 2.5.1.18,5.3.99.2 0000287,0001516,0004364,0004667,0005509,0005515,0005654,0005737,0005829,0006693,0007165,0007626,0009624,0010269,0016740,0016853,0042803,0043231,0046872,2000255 O60760 18341273 1202 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 2vd1 C 2.25 BS01 GSH C 1 Y8 R14 W39 K43 K50 I51 Q63 S64 Y7 R13 W38 K42 K49 I50 Q62 S63 Y8 R14 R19 Y7 R13 R18 2.5.1.18,5.3.99.2 0000287,0001516,0004364,0004667,0005509,0005515,0005654,0005737,0005829,0006693,0007165,0007626,0009624,0010269,0016740,0016853,0042803,0043231,0046872,2000255 O60760 18341273 1200 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 2vd1 D 2.25 BS01 GSH D 1 Y8 R14 W39 K43 K50 I51 Q63 S64 Y7 R13 W38 K42 K49 I50 Q62 S63 Y8 R14 R19 W104 Y7 R13 R18 W103 2.5.1.18,5.3.99.2 0000287,0001516,0004364,0004667,0005509,0005515,0005654,0005737,0005829,0006693,0007165,0007626,0009624,0010269,0016740,0016853,0042803,0043231,0046872,2000255 O60760 18341273 1200 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL