2rfn A 2.5 BS01 AM7 A 1 I1084 F1089 V1092 A1108 K1110 F1124 E1127 G1128 M1131 L1140 L1142 V1155 L1157 Y1159 M1160 K1161 G1163 M1211 I28 F29 V32 A48 K50 F64 E67 G68 M71 L80 L82 V95 L97 Y99 M100 K101 G103 M151 D1204 A1206 R1208 N1209 D1222 D144 A146 R148 N149 D162 2.7.10.1 0004672,0004713,0005524,0006468 ic50=5nM -logKd/Ki=8.30, IC50=5nM IC50=8.9nM, Ki=8.9nM P08581 18055465 1 ALNPELVQAVQHVVIGPSSLIVHFNEVIFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVH 2rfn B 2.5 BS01 AM7 B 1 I1084 F1089 V1092 A1108 F1124 E1127 M1131 L1142 L1157 Y1159 M1160 K1161 G1163 M1211 I29 F30 V33 A49 F65 E68 M72 L83 L98 Y100 M101 K102 G104 M152 D1204 A1206 R1208 N1209 D1222 D145 A147 R149 N150 D163 2.7.10.1 0004672,0004713,0005524,0006468 ic50=5nM IC50=8.9nM, Ki=8.9nM P08581 18055465 1 SALNPELVQAVQHVVIGPSSLIVHFNEVIFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVH