2r4b A 2.4 BS01 GW7 A 1 A749 K751 M772 V781 L783 L794 T796 M799 C803 L850 T860 D861 F862 A56 K58 M73 V82 L84 L95 T97 M100 C104 L151 T161 D162 F163 D843 A845 R847 N848 D861 G880 D144 A146 R148 N149 D162 G181 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=7.18, IC50=66nM Q15303 18287036 1 LVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDD 2r4b B 2.4 BS01 GW7 B 1 A749 K751 M772 V781 L783 L794 T796 M799 C803 L850 T860 D861 F862 A56 K58 M72 V81 L83 L94 T96 M99 C103 L150 T160 D161 F162 D843 A845 R847 N848 D861 G880 D143 A145 R147 N148 D161 G180 2.7.10.1 0004672,0004713,0005524,0006468 Q15303 18287036 1 LVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDD