2r2m B 2.1 BS01 peptide A 0 E44 G46 M47 P49 W50 D149 H152 P153 C155 Y170 K171 R173 N194 M241 K242 N247 R248 W249 E8 G10 M11 P13 W14 D113 H116 P117 C119 Y134 K135 R137 N156 M203 K204 N209 R210 W211 H79 D135 E232 G233 D234 S235 G236 H43 D99 E194 G195 D196 S197 G198 3.4.21.5 0004252,0005509,0006508,0007596 P00734 17889527 7 ~ 32 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 2r2m B 2.1 BS02 peptide H 0 F55 Q60 L62 R104 T105 R106 Y107 M116 F19 Q24 L26 R68 T69 R70 Y71 M80 H79 D135 E232 G233 D234 S235 G236 H43 D99 E194 G195 D196 S197 G198 3.4.21.5 0004252,0005509,0006508,0007596 P00734 17889527 290 ~ 300 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 2r2m B 2.1 BS03 I50 B 1 H79 Y83 W86 E130 D229 A230 C231 S235 S256 W257 G258 H43 Y47 W50 E94 D191 A192 C193 S197 S218 W219 G220 H79 D135 E232 G233 D234 S235 G236 H43 D99 E194 G195 D196 S197 G198 3.4.21.5 0004252,0005509,0006508,0007596 Ki=47.1nM -logKd/Ki=7.33, Ki=47.1nM P00734 17889527 5000 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF