2qwx A 1.5 BS01 ZN A 1 H173 H177 C222 H173 H177 C222 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 18254726 231 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx A 1.5 BS02 FAD A 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 Y155 E193 R200 K201 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 Y155 E193 R200 K201 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 18254726 232 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx A 1.5 BS03 ML1 A 1 F126 F178 F126 F178 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 Kd=1.4uM IC50=11300nM, Ki=57nM P16083 18254726 233 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx A 1.5 BS04 ML1 B 1 W105 M154 W105 M154 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 Kd=1.4uM IC50=11300nM, Ki=57nM P16083 18254726 233 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx B 1.5 BS01 ML1 A 1 W105 G149 W105 G149 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 Kd=1.4uM IC50=11300nM, Ki=57nM P16083 18254726 233 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx B 1.5 BS02 ZN B 1 H173 H177 C222 H173 H177 C222 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 18254726 231 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx B 1.5 BS03 FAD B 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 E197 R200 K201 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 E197 R200 K201 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 18254726 232 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 2qwx B 1.5 BS04 ML1 B 1 F126 F178 F126 F178 G149 Y155 N161 G149 Y155 N161 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 Kd=1.4uM IC50=11300nM, Ki=57nM P16083 18254726 233 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ