2obf A 2.3 BS01 F83 A 1 Y35 N39 Y40 R44 V53 G54 L58 Y85 Y126 F182 E219 Y222 Y12 N16 Y17 R21 V30 G31 L35 Y62 Y103 F159 E196 Y199 2.1.1.28 0004603,0005515,0005829,0008168,0032259,0042418,0042423 Ki=1.4nM -logKd/Ki=8.85, Ki=1.4nM Ki=63nM P11086 17845018 2001 ASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWALRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKV 2obf A 2.3 BS02 SAH A 1 Y27 Y35 Y40 S80 T83 Y85 D101 F102 L103 N106 D158 V159 H160 A181 F182 C183 V187 Y4 Y12 Y17 S57 T60 Y62 D78 F79 L80 N83 D135 V136 H137 A158 F159 C160 V164 2.1.1.28 0004603,0005515,0005829,0008168,0032259,0042418,0042423 P11086 17845018 3001 ASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWALRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKV 2obf B 2.3 BS01 F83 B 1 Y535 N539 Y540 R544 V553 G554 L558 Y626 F682 E719 Y722 D767 Y22 N26 Y27 R31 V40 G41 L45 Y113 F169 E206 Y209 D254 2.1.1.28 0004603,0005515,0005829,0008168,0032259,0042418,0042423 Ki=1.4nM Ki=63nM P11086 17845018 2002 PDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWALRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL 2obf B 2.3 BS02 SAH B 1 Y527 Y535 Y540 S580 G581 T583 Y585 D601 F602 L603 N606 D658 V659 A681 F682 C683 V687 Y14 Y22 Y27 S67 G68 T70 Y72 D88 F89 L90 N93 D145 V146 A168 F169 C170 V174 2.1.1.28 0004603,0005515,0005829,0008168,0032259,0042418,0042423 P11086 17845018 3002 PDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWALRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL