2o4h A 2.7 BS01 ZN A 1 H21 E24 H116 H12 E15 H107 3.5.1.15 0005515,0005634,0005737,0005829,0006083,0006531,0016787,0016788,0016811,0019807,0022010,0042802,0046872,0048714 P45381 18293939 401 HIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKKCTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKSIRC 2o4h A 2.7 BS02 AS9 A 1 H21 E24 R63 N70 R71 H116 N117 I127 Y164 R168 E178 E285 Y288 H12 E15 R54 N61 R62 H107 N108 I118 Y155 R159 E169 E276 Y279 3.5.1.15 0005515,0005634,0005737,0005829,0006083,0006531,0016787,0016788,0016811,0019807,0022010,0042802,0046872,0048714 -logKd/Ki=6.52, Ki=300nM P45381 18293939 501 HIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKKCTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKSIRC 2o4h B 2.7 BS01 ZN B 1 H21 E24 H116 H12 E15 H107 3.5.1.15 0005515,0005634,0005737,0005829,0006083,0006531,0016787,0016788,0016811,0019807,0022010,0042802,0046872,0048714 P45381 18293939 401 HIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKKCTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKSIRC 2o4h B 2.7 BS02 AS9 B 1 H21 R63 N70 R71 H116 Y164 R168 E178 E285 Y288 H12 R54 N61 R62 H107 Y155 R159 E169 E276 Y279 3.5.1.15 0005515,0005634,0005737,0005829,0006083,0006531,0016787,0016788,0016811,0019807,0022010,0042802,0046872,0048714 P45381 18293939 501 HIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKKCTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKSIRC