2nyr A 2.06 BS01 ZN A 1 C166 C169 C207 C212 C131 C134 C172 C177 P68 T69 F70 R71 N141 D143 H158 P33 T34 F35 R36 N106 D108 H123 2.3.1.- 0036054,0036055,0070403 Q9NXA8 17355872 501 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTERFHFQGPCGTTLPEALA 2nyr A 2.06 BS02 SVR B 1 T69 F70 R71 A82 F101 Y102 R105 N141 I142 F223 Y255 M259 T34 F35 R36 A47 F66 Y67 R70 N106 I107 F188 Y220 M224 P68 T69 F70 R71 N141 D143 H158 P33 T34 F35 R36 N106 D108 H123 2.3.1.- 0036054,0036055,0070403 -logKd/Ki=4.66, IC50=22uM IC50=25000nM Q9NXA8 17355872 401 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTERFHFQGPCGTTLPEALA 2nyr B 2.06 BS01 SVR B 1 F70 R71 A86 Y102 R105 H158 V221 F223 G224 E225 N226 L232 V254 Y255 F35 R36 A51 Y67 R70 H123 V186 F188 G189 E190 N191 L197 V219 Y220 P68 T69 F70 R71 N141 D143 H158 P33 T34 F35 R36 N106 D108 H123 2.3.1.- 0036054,0036055,0070403 -logKd/Ki=4.66, IC50=22uM IC50=25000nM Q9NXA8 17355872 401 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTRFHFQGPCGTTLPEALA 2nyr B 2.06 BS02 ZN B 1 C166 C169 C207 C212 C131 C134 C172 C177 P68 T69 F70 R71 N141 D143 H158 P33 T34 F35 R36 N106 D108 H123 2.3.1.- 0036054,0036055,0070403 Q9NXA8 17355872 501 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTRFHFQGPCGTTLPEALA