2np8 A 2.25 BS01 CC3 A 1 L139 G142 K143 V147 A160 L194 A213 P214 G216 L263 L13 G16 K17 V21 A34 L68 A87 P88 G90 L137 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T160 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 ic50=42nM -logKd/Ki=7.38, IC50=42nM IC50=42nM O14965 17157005 394 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS