2jjo A 1.99 BS01 HEM A 1 H95 R99 F106 L238 A241 G242 T245 T246 L249 M291 R293 S345 F346 H351 C353 L354 G355 A359 H77 R81 F88 L220 A223 G224 T227 T228 L231 M273 R275 S327 F328 H333 C335 L336 G337 A341 D171 A241 I244 T245 T246 C353 L354 G355 E362 V393 D153 A223 I226 T227 T228 C335 L336 G337 E344 V375 1.14.13.154 0004497,0005506,0016705,0016709,0017000,0020037,0033068,0046872,0050661 P48635 19625248 412 DEVPGMADETALLDWLGTMREKQPVWQDRYGVWHVFRHADVQTVLRDTATFSSDPTRVIEGASPTPGMIHEIDPPEHRALRKVVSSAFTPRTISDLEPRIRDVTRSLLADAGESFDLVDVLAFPLPVTIVAELLGLPPMDHEQFGDWSGALVDIQMDDPTDPALAERIADVLNPLTAYLKARCAERRADPGDDLISRLVLAEVDGRALDDEEAANFSTALLLAGHITTTVLLGNIVRTLDEHPAHWDAAAEDPGRIPAIVEEVLRYRPPFPQMQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSRKSGGAAQLSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVDRDDERLRHFEQIVLGTRHLPVLAGSSPRQSA 2jjo A 1.99 BS02 EY5 A 1 H88 E89 L169 M174 I186 A237 A241 T245 F288 Q292 H70 E71 L151 M156 I168 A219 A223 T227 F270 Q274 D171 A241 I244 T245 T246 C353 L354 G355 E362 V393 D153 A223 I226 T227 T228 C335 L336 G337 E344 V375 1.14.13.154 0004497,0005506,0016705,0016709,0017000,0020037,0033068,0046872,0050661 Kd=3.5uM P48635 19625248 413 DEVPGMADETALLDWLGTMREKQPVWQDRYGVWHVFRHADVQTVLRDTATFSSDPTRVIEGASPTPGMIHEIDPPEHRALRKVVSSAFTPRTISDLEPRIRDVTRSLLADAGESFDLVDVLAFPLPVTIVAELLGLPPMDHEQFGDWSGALVDIQMDDPTDPALAERIADVLNPLTAYLKARCAERRADPGDDLISRLVLAEVDGRALDDEEAANFSTALLLAGHITTTVLLGNIVRTLDEHPAHWDAAAEDPGRIPAIVEEVLRYRPPFPQMQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSRKSGGAAQLSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVDRDDERLRHFEQIVLGTRHLPVLAGSSPRQSA