2isv A 2.3 BS01 ZN A 1 H84 H178 H210 H83 H163 H186 4.1.2.13 0004332,0005515,0005975,0006096,0008270,0016829,0016832,0046872 A8B2U2 17166851 326 PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKYSDMIYLKKLCEAALEKHPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGLTEPQDAKKFVELTGVDALAVAIGTSHGARLAIDRVKTISDLTGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHAGDYKVVSLEEAKAWY 2isv A 2.3 BS02 PGH A 1 D83 H178 H210 G211 S213 N253 D255 S256 D82 H163 H186 G187 S189 N229 D231 S232 4.1.2.13 0004332,0005515,0005975,0006096,0008270,0016829,0016832,0046872 Ki=37nM -logKd/Ki=7.43, Ki=37nM A8B2U2 17166851 325 PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKYSDMIYLKKLCEAALEKHPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGLTEPQDAKKFVELTGVDALAVAIGTSHGARLAIDRVKTISDLTGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHAGDYKVVSLEEAKAWY 2isv B 2.3 BS01 ZN B 1 H84 H178 H210 H83 H168 H195 4.1.2.13 0004332,0005515,0005975,0006096,0008270,0016829,0016832,0046872 A8B2U2 17166851 326 PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKYSDMIYLKKLCEAALEKHPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGQNTVQLTEPQDAKKFVELTGVDALAVAIGTSHGAYKFIRLAIDRVKTISDLTGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHAGDYKVVSLEEAKAWY 2isv B 2.3 BS02 PGH B 1 D83 H178 G179 K182 H210 G211 S213 N253 D255 S256 D82 H168 G169 K172 H195 G196 S198 N238 D240 S241 4.1.2.13 0004332,0005515,0005975,0006096,0008270,0016829,0016832,0046872 Ki=37nM -logKd/Ki=7.43, Ki=37nM A8B2U2 17166851 325 PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKYSDMIYLKKLCEAALEKHPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGQNTVQLTEPQDAKKFVELTGVDALAVAIGTSHGAYKFIRLAIDRVKTISDLTGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHAGDYKVVSLEEAKAWY