2iok A 2.4 BS01 IOK A 1 M343 A350 E353 L384 F404 L428 H524 L525 M31 A38 E41 L72 F92 L116 H212 L213 ? ic50=1nM -logKd/Ki=9.00, IC50=1nM IC50=1nM P03372 17289385 600 LALSLTADQMVSALLDAEPPILYSEYEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKPLYDLLLEML 2iok B 2.4 BS01 IOK B 1 L1349 E1353 M1421 G1521 H1524 L1525 L40 E44 M112 G212 H215 L216 ? ic50=1nM IC50=1nM P03372 17289385 1600 LALSLTADQMVSALLDAEPPILYSEYDPTRASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSPLYDLLLEML