2il2 A 2.24 BS01 LIX A 1 T13 Q14 Y15 V31 D33 G35 Y78 S79 T80 L116 F119 V122 D221 G223 S225 F248 H296 T16 Q17 Y18 V34 D36 G38 Y81 S82 T83 L119 F122 V125 D224 G226 S228 F251 H299 D33 S36 N38 W40 Y78 D221 A224 D36 S39 N41 W43 Y81 D224 A227 3.4.23.15 0004190,0006508 Kd=79nM IC50=27nM, Kd=79nM P00797 17113558 401 LGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 2il2 B 2.24 BS01 LIX B 1 T13 Q14 Y15 V31 D33 Y78 S79 T80 L116 V122 D221 G223 A224 S225 Y226 H296 M298 T16 Q17 Y18 V34 D36 Y81 S82 T83 L119 V125 D224 G226 A227 S228 Y229 H299 M301 D33 S36 N38 W40 Y78 D221 A224 D36 S39 N41 W43 Y81 D224 A227 3.4.23.15 0004190,0006508 Kd=79nM -logKd/Ki=7.10, Kd=79nM IC50=27nM, Kd=79nM P00797 17113558 402 LGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR