2hu6 A 1.32 BS01 ZN A 1 H218 H222 H228 H113 H117 H123 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 264 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS02 ZN A 2 H168 D170 H183 H196 H63 D65 H78 H91 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 265 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS03 CA A 1 D158 G190 G192 D194 D53 G85 G87 D89 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 266 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS04 CA A 2 D124 E199 E201 D19 E94 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 267 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS05 CA A 3 D175 G176 G178 I180 D198 E201 D70 G71 G73 I75 D93 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 268 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS06 37A A 1 G179 I180 L181 H218 V235 F237 P238 T239 Y240 K241 G74 I75 L76 H113 V130 F132 P133 T134 Y135 K136 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 Kd=154uM -logKd/Ki=3.81, Kd=154uM IC50=149000nM, Kd=154000nM P39900 16899369 400 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 2hu6 A 1.32 BS07 HAE A 1 A182 H218 E219 H222 H228 A77 H113 E114 H117 H123 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 16899369 269 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG