2gie A 2.6 BS01 dna E 0 H73 Y77 S90 K93 Q109 Q138 Y199 N201 A204 R241 K248 H72 Y76 S89 K92 Q108 Q137 Y198 N200 A203 R240 K247 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL 2gie A 2.6 BS02 dna F 0 G30 H31 Q109 N110 D114 D127 K129 T130 N132 S136 A137 Q138 P140 N141 S144 Y146 K147 A205 M206 Q207 G29 H30 Q108 N109 D113 D126 K128 T129 N131 S135 A136 Q137 P139 N140 S143 Y145 K146 A204 M205 Q206 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL 2gie B 2.6 BS01 dna E 0 G30 H31 Q109 N110 D127 K129 T130 R131 N132 K135 S136 A137 Q138 A139 P140 N141 S144 K147 A205 Q207 G29 H30 Q108 N109 D126 K128 T129 R130 N131 K134 S135 A136 Q137 A138 P139 N140 S143 K146 A204 Q206 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI 2gie B 2.6 BS02 dna F 0 Y77 L86 S90 G92 K93 K108 Q109 Q138 Y199 N201 A204 Y76 L85 S89 G91 K92 K107 Q108 Q137 Y198 N200 A203 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI 2gie C 2.6 BS01 dna G 0 Y77 R91 G92 K93 A94 K108 Q109 Q138 Y199 N201 A204 Y76 R90 G91 K92 A93 K107 Q108 Q137 Y198 N200 A203 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL 2gie C 2.6 BS02 dna H 0 G30 H31 Q109 N110 D114 D127 K129 T130 N132 K135 A137 Q138 P140 N141 I143 S144 Y146 K147 A205 Q207 G29 H30 Q108 N109 D113 D126 K128 T129 N131 K134 A136 Q137 P139 N140 I142 S143 Y145 K146 A204 Q206 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL 2gie D 2.6 BS01 dna G 0 G30 H31 A33 Q109 N110 D111 D114 T130 N132 K135 S136 A137 Q138 P140 N141 S144 K147 A205 G29 H30 A32 Q108 N109 D110 D113 T129 N131 K134 S135 A136 Q137 P139 N140 S143 K146 A204 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI 2gie D 2.6 BS02 dna H 0 Y77 G92 K93 K108 Q109 Q138 Y199 N201 K248 Y76 G91 K92 K107 Q108 Q137 Y198 N200 K247 3.1.21.4 0003677,0004519,0009036,0009307 Kd=0.58nM P17743 16675462 1 ~ 13 SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI