2fzg A 2.25 BS01 EOB A 1 S52 R54 T55 R105 H134 R167 T168 R229 P266 L267 S52 R54 T55 R105 H134 R167 T168 R229 P266 L267 R54 T55 K84 R105 H134 Q137 T228 P266 G292 R54 T55 K84 R105 H134 Q137 T228 P266 G292 2.1.3.2 0004070,0004088,0005515,0005737,0005829,0006207,0006221,0006520,0006541,0009347,0016597,0016740,0016743,0042802,0044205,0070207 Ki=420uM -logKd/Ki=3.38, Ki=420uM P0A786 16906764 611 ANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL 2fzg B 2.25 BS01 ZN B 1 C109 C114 C141 C108 C113 C140 2.1.3.2 0005515,0005737,0006207,0006221,0008270,0009347,0046872 P0A7F3 16906764 154 THDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN 2fzg B 2.25 BS02 CTP B 1 T2 D4 A11 I12 V17 H20 K60 I86 Y89 V91 K94 T1 D3 A10 I11 V16 H19 K59 I85 Y88 V90 K93 2.1.3.2 0005515,0005737,0006207,0006221,0008270,0009347,0046872 P0A7F3 16906764 901 THDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN 2fzg C 2.25 BS01 EOB C 1 S52 T53 R54 T55 R105 H134 Q137 T168 R229 S52 T53 R54 T55 R105 H134 Q137 T168 R229 R54 T55 K84 R105 H134 Q137 T228 P266 G292 R54 T55 K84 R105 H134 Q137 T228 P266 G292 2.1.3.2 0004070,0004088,0005515,0005737,0005829,0006207,0006221,0006520,0006541,0009347,0016597,0016740,0016743,0042802,0044205,0070207 Ki=420uM P0A786 16906764 612 ANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL 2fzg D 2.25 BS01 ZN D 1 C109 C114 C138 C141 C108 C113 C137 C140 2.1.3.2 0005515,0005737,0006207,0006221,0008270,0009347,0046872 P0A7F3 16906764 154 THDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN 2fzg D 2.25 BS02 CTP D 1 A11 I12 V17 H20 K60 I86 Y89 A10 I11 V16 H19 K59 I85 Y88 2.1.3.2 0005515,0005737,0006207,0006221,0008270,0009347,0046872 P0A7F3 16906764 902 THDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN