2f0y A 2.7 BS01 FPP B 1 K164 Y166 H201 K110 Y112 H147 K164 K110 2.5.1.58,2.5.1.59 0004659,0004660,0004661,0004662,0004663,0005515,0005737,0005829,0005875,0005886,0005953,0005965,0007167,0007179,0007528,0008017,0008318,0018342,0018343,0018344,0030971,0035022,0043014,0060090,0071340,0090044,0090045,1904395 Kd=2.0nM P49354 1001 FVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHS 2f0y B 2.7 BS01 ZN B 1 D297 C299 H362 D271 C273 H336 H248 R291 K294 D297 C299 Y300 D352 D359 H362 H222 R265 K268 D271 C273 Y274 D326 D333 H336 2.5.1.58 0003824,0004659,0004660,0005515,0005829,0005875,0005965,0006629,0008270,0008318,0018343,0046872 P49356 501 EPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVP 2f0y B 2.7 BS02 FPP B 1 H248 G250 C254 R291 K294 Y300 W303 H222 G224 C228 R265 K268 Y274 W277 H248 R291 K294 D297 C299 Y300 D352 D359 H362 H222 R265 K268 D271 C273 Y274 D326 D333 H336 2.5.1.58 0003824,0004659,0004660,0005515,0005829,0005875,0005965,0006629,0008270,0008318,0018343,0046872 P49356 1001 EPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVP 2f0y B 2.7 BS03 3MN B 1 L96 W102 D297 Y300 D359 Y361 L70 W76 D271 Y274 D333 Y335 H248 R291 K294 D297 C299 Y300 D352 D359 H362 H222 R265 K268 D271 C273 Y274 D326 D333 H336 2.5.1.58 0003824,0004659,0004660,0005515,0005829,0005875,0005965,0006629,0008270,0008318,0018343,0046872 IC50=0.09nM P49356 963 EPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVP