2e2b A 2.2 BS01 406 A 1 L248 Y253 A269 K271 E286 V289 M290 L298 I313 T315 F317 M318 I360 H361 V379 A380 D381 F382 L24 Y29 A45 K47 E58 V61 M62 L70 I85 T87 F89 M90 I132 H133 V151 A152 D153 F154 D363 A365 R367 N368 D381 P402 D135 A137 R139 N140 D153 P170 2.7.10.2 0004672,0004713,0005524,0006468 ic50=11nM -logKd/Ki=7.96, IC50=11nM IC50=4.0nM P00519 17376680 1001 MDPSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI 2e2b B 2.2 BS01 406 B 1 L248 Y253 V256 A269 K271 E286 V289 M290 L298 I313 T315 F317 M318 I360 H361 R362 A380 D381 F382 L24 Y29 V32 A45 K47 E57 V60 M61 L69 I84 T86 F88 M89 I131 H132 R133 A151 D152 F153 D363 A365 R367 N368 D381 P402 D134 A136 R138 N139 D152 P167 2.7.10.2 0004672,0004713,0005524,0006468 ic50=11nM IC50=4.0nM P00519 17376680 1002 MDPSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMF