2bys A 2.05 BS01 LOB A 1 Y93 G145 S146 W147 Y188 C190 C191 Y195 Y90 G142 S143 W144 Y185 C187 C188 Y192 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM -logKd/Ki=9.52, Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys A 2.05 BS02 LOB B 1 Y55 V108 M116 I118 Y52 V105 M113 I115 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM -logKd/Ki=9.52, Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys B 2.05 BS01 LOB B 1 G145 S146 W147 Y188 C190 C191 Y195 G143 S144 W145 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys B 2.05 BS02 LOB C 1 Y55 V108 M116 I118 Y53 V106 M114 I116 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys C 2.05 BS01 LOB C 1 Y93 G145 S146 W147 Y188 C191 Y195 Y88 G140 S141 W142 Y183 C186 Y190 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys C 2.05 BS02 LOB D 1 Y55 V108 M116 I118 Y50 V103 M111 I113 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys D 2.05 BS01 LOB D 1 G145 S146 W147 Y188 C190 C191 Y195 G142 S143 W144 Y185 C187 C188 Y192 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys D 2.05 BS02 LOB E 1 Y55 V108 M116 I118 Y52 V105 M113 I115 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys E 2.05 BS01 LOB A 1 Y55 V108 M116 I118 Y53 V106 M114 I116 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM -logKd/Ki=9.52, Kd=0.3nM Q8WSF8 16193063 301 KLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys E 2.05 BS02 LOB E 1 Y93 G145 S146 W147 Y188 C191 Y195 Y91 G143 S144 W145 Y186 C189 Y193 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM -logKd/Ki=9.52, Kd=0.3nM Q8WSF8 16193063 301 KLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys F 2.05 BS01 LOB F 1 Y93 G145 S146 W147 Y188 C190 C191 Y195 Y89 G141 S142 W143 Y184 C186 C187 Y191 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys F 2.05 BS02 LOB G 1 Y55 V108 M116 I118 Y51 V104 M112 I114 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys G 2.05 BS01 LOB G 1 G145 S146 W147 Y188 C190 C191 Y195 G140 S141 W142 Y183 C185 C186 Y190 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 HSQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys G 2.05 BS02 LOB H 1 Y55 V108 M116 I118 Y50 V103 M111 I113 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 HSQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys H 2.05 BS01 LOB H 1 Y93 G145 S146 W147 Y188 C190 C191 Y195 Y90 G142 S143 W144 Y185 C187 C188 Y192 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 HSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2bys H 2.05 BS02 LOB I 1 Y55 V108 M116 I118 Y52 V105 M113 I115 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 HSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2bys I 2.05 BS01 LOB I 1 G145 S146 W147 Y188 C190 C191 Y195 G143 S144 W145 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys I 2.05 BS02 LOB J 1 Y55 V108 M116 I118 Y53 V106 M114 I116 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys J 2.05 BS01 LOB F 1 Y55 V108 M116 I118 Y51 V104 M112 I114 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2bys J 2.05 BS02 LOB J 1 Y93 G145 S146 W147 Y188 C191 Y195 Y89 G141 S142 W143 Y184 C187 Y191 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=0.3nM Q8WSF8 16193063 301 SQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR