2byr A 2.45 BS01 MLK A 1 Y93 S94 K143 W147 V148 Y188 C190 Y195 Y98 S99 K148 W152 V153 Y193 C195 Y200 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM -logKd/Ki=8.55, Kd=2.8nM Q8WSF8 16193063 301 DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr A 2.45 BS02 MLK B 1 M116 I118 S167 M121 I123 S172 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM -logKd/Ki=8.55, Kd=2.8nM Q8WSF8 16193063 301 DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr B 2.45 BS01 MLK B 1 Y93 S94 K143 W147 V148 Y149 Y188 Y195 Y94 S95 K144 W148 V149 Y150 Y189 Y196 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRA 2byr B 2.45 BS02 MLK C 1 Y55 S167 Y56 S168 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRA 2byr C 2.45 BS01 MLK C 1 Y93 S94 K143 W147 V148 Y188 C190 Y195 D197 Y95 S96 K145 W149 V150 Y190 C192 Y197 D199 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DKLHSQANLMRLKSDLFNRPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr D 2.45 BS01 MLK D 1 Y93 S94 K143 W147 V148 Y188 C190 Y195 Y96 S97 K146 W150 V151 Y191 C193 Y198 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr E 2.45 BS01 MLK A 1 I118 S167 I124 S173 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM -logKd/Ki=8.55, Kd=2.8nM Q8WSF8 16193063 301 DDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr E 2.45 BS02 MLK E 1 Y93 S94 K143 W147 V148 Y188 C190 Y195 Y99 S100 K149 W153 V154 Y194 C196 Y201 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM -logKd/Ki=8.55, Kd=2.8nM Q8WSF8 16193063 301 DDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr F 2.45 BS01 MLK F 1 Y93 S94 K143 W147 V148 Y149 Q186 Y188 Y195 Y94 S95 K144 W148 V149 Y150 Q187 Y189 Y196 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr F 2.45 BS02 MLK G 1 Y55 I118 S167 Y56 I119 S168 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr G 2.45 BS01 MLK G 1 Y93 S94 K143 W147 V148 Q186 Y188 C190 Y195 D197 Y91 S92 K141 W145 V146 Q184 Y186 C188 Y193 D195 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2byr G 2.45 BS02 MLK H 1 Y55 I118 S167 Y53 I116 S165 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2byr H 2.45 BS01 MLK H 1 Y93 S94 K143 W147 V148 Y149 Q186 Y188 C190 Y195 Y90 S91 K140 W144 V145 Y146 Q183 Y185 C187 Y192 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 HSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2byr H 2.45 BS02 MLK I 1 M116 I118 S167 M113 I115 S164 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 HSQANLMRLKSDLFNRYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 2byr I 2.45 BS01 MLK I 1 Y93 K143 W147 V148 Y149 Q186 Y188 Y195 Y98 K148 W152 V153 Y154 Q191 Y193 Y200 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DDDDKLHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr I 2.45 BS02 MLK J 1 I118 S167 I123 S172 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DDDDKLHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr J 2.45 BS01 MLK F 1 I118 S167 I122 S171 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 2byr J 2.45 BS02 MLK J 1 Y93 S94 K143 W147 V148 Y149 Y188 Y195 Y97 S98 K147 W151 V152 Y153 Y192 Y199 ? 0004888,0005216,0005230,0006811,0016020,0034220 Kd=2.8nM Q8WSF8 16193063 301 DDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR