2bt4 A 1.7 BS01 CA2 A 1 N16 L19 R23 Y28 N79 A81 A82 H85 H106 I107 S108 R117 N15 L18 R22 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 160 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 B 1.7 BS01 CA2 B 1 N216 L217 L219 L220 R223 Y228 N279 A281 A282 H285 H306 I307 S308 R317 N15 L16 L18 L19 R22 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 360 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 C 1.7 BS01 CA2 C 1 N416 L417 L419 L420 Y428 N479 A481 A482 H485 H506 I507 S508 R517 N15 L16 L18 L19 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 560 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 D 1.7 BS01 CA2 D 1 N616 L619 Y628 N679 A681 A682 H685 H706 I707 S708 R717 N15 L18 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 760 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 E 1.7 BS01 CA2 E 1 N816 L817 L819 L820 R823 Y828 N879 A881 A882 H906 I907 S908 R917 N15 L16 L18 L19 R22 Y27 N78 A80 A81 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 960 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 F 1.7 BS01 CA2 F 1 N1016 L1019 R1023 Y1028 N1079 A1081 A1082 H1085 H1106 I1107 S1108 R1117 N15 L18 R22 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 1160 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 G 1.7 BS01 CA2 G 1 N1216 L1217 L1219 L1220 R1223 Y1228 N1279 A1281 A1282 H1285 H1306 I1307 S1308 R1317 N15 L16 L18 L19 R22 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 1360 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 H 1.7 BS01 CA2 H 1 N1416 L1419 L1420 R1423 Y1428 N1479 A1481 A1482 H1485 H1506 I1507 S1508 R1517 N15 L18 L19 R22 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 1560 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 I 1.7 BS01 CA2 I 1 N1616 L1619 L1620 Y1628 N1679 A1681 A1682 H1685 H1706 I1707 S1708 R1717 N15 L18 L19 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 1760 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 J 1.7 BS01 CA2 J 1 N1816 L1819 L1820 Y1828 N1879 A1881 A1882 H1885 H1906 I1907 S1908 R1917 N15 L18 L19 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 1960 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 K 1.7 BS01 CA2 K 1 N2016 L2017 L2019 L2020 Y2028 N2079 A2081 A2082 H2085 H2106 I2107 S2108 R2117 N15 L16 L18 L19 Y27 N78 A80 A81 H84 H105 I106 S107 R116 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 2160 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG 2bt4 L 1.7 BS01 CA2 L 1 N2216 L2219 L2220 Y2228 N2279 A2281 A2282 H2285 H2306 I2307 S2308 R2317 N15 L18 L19 Y27 N78 A80 A81 H84 H105 I106 S107 R116 P2215 N2216 R2223 Y2228 N2279 A2282 E2304 H2306 R2313 P14 N15 R22 Y27 N78 A81 E103 H105 R112 4.2.1.10 0003855,0008652,0009073,0009423,0016829,0019631 Ki=33uM P15474 16106291 2360 RSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAG