1y57 A 1.91 BS01 MPZ A 1 L273 Q275 V281 A293 Y340 M341 G344 L393 L192 Q194 V200 A212 Y259 M260 G263 L312 D386 R388 A390 N391 D404 F424 D305 R307 A309 N310 D323 F343 2.7.10.2 0004672,0004713,0005524,0006468 ic50=1633nM -logKd/Ki=5.79, IC50=1633nM IC50=7800nM P12931 15939018 600 MVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL