1xge A 1.9 BS01 ZN A 1 K102 H139 H177 K99 H136 H174 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 P05020 15826651 400 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK 1xge A 1.9 BS02 ZN A 2 H16 H18 K102 D250 H13 H15 K99 D247 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 P05020 15826651 401 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK 1xge A 1.9 BS03 DOR A 1 H18 R20 H139 C221 L222 A252 H254 A266 G267 H15 R17 H136 C218 L219 A249 H251 A263 G264 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 Kd=20.8uM -logKd/Ki=4.68, Kd=20.8uM P05020 15826651 1410 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK 1xge B 1.9 BS01 ZN B 1 K102 H139 H177 K99 H136 H174 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 P05020 15826651 400 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK 1xge B 1.9 BS02 ZN B 2 H16 H18 K102 D250 H13 H15 K99 D247 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 P05020 15826651 401 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK 1xge B 1.9 BS03 NCD B 1 H18 R20 K102 T109 T110 H139 H177 C221 L222 D250 A252 A266 G267 H15 R17 K99 T106 T107 H136 H174 C218 L219 D247 A249 A263 G264 H16 H18 K102 H139 H177 D250 H13 H15 K99 H136 H174 D247 3.5.2.3 0004151,0005737,0005829,0006207,0006221,0008270,0016787,0016812,0019856,0042803,0044205,0046872 P05020 15826651 2410 SQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVK