1x7b A 2.3 BS01 peptide C 0 I310 K314 V328 D489 E493 I48 K52 V66 D217 E221 ? 0003677,0004879,0006355 Q92731 15548008 604 ~ 613 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 1x7b A 2.3 BS02 041 A 1 M295 E305 L339 M340 L343 I373 I376 H475 L476 M33 E43 L77 M78 L81 I111 I114 H203 L204 ? 0003677,0004879,0006355 ic50=4.1nM -logKd/Ki=8.39, IC50=4.1nM IC50=5nM Q92731 15548008 201 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 1x7b B 2.3 BS01 peptide D 0 I310 K314 V328 L490 E493 I48 K52 V66 L218 E221 ? 0003677,0004879,0006355 Q92731 15548008 604 ~ 613 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNA 1x7b B 2.3 BS02 041 B 1 M295 E305 L339 M340 L343 I376 F377 H475 L476 M33 E43 L77 M78 L81 I114 F115 H203 L204 ? 0003677,0004879,0006355 ic50=4.1nM IC50=5nM Q92731 15548008 202 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNA