1u3r A 2.21 BS01 peptide C 0 I310 K314 E493 I48 K52 E224 ? 0003677,0004879,0006355 Q92731 15456246 605 ~ 613 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 1u3r A 2.21 BS02 338 A 1 L298 E305 L339 L343 F356 I373 H475 L476 L36 E43 L77 L81 F94 I111 H206 L207 ? 0003677,0004879,0006355 ic50=5nM -logKd/Ki=8.30, IC50=5nM IC50=5nM Q92731 15456246 201 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 1u3r B 2.21 BS01 peptide D 0 I310 K314 V328 E493 I48 K52 V66 E219 ? 0003677,0004879,0006355 Q92731 15456246 605 ~ 613 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLR 1u3r B 2.21 BS02 338 B 1 L298 E305 L339 F356 H475 L476 L36 E43 L77 F94 H201 L202 ? 0003677,0004879,0006355 ic50=5nM IC50=5nM Q92731 15456246 202 LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLR