1u1c A 2.2 BS01 PO4 A 1 G26 R30 R91 G93 T94 E198 G26 R30 R91 G93 T94 E198 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3030 MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c A 2.2 BS02 BAU A 1 T94 T95 G96 F162 Q166 R168 E196 I220 P229 T94 T95 G96 F162 Q166 R168 E196 I220 P229 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5400 MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c A 2.2 BS03 BAU B 1 F7 H8 F7 H8 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5011 MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c B 2.2 BS01 BAU A 1 F7 H8 F5 H6 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5400 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c B 2.2 BS02 PO4 B 1 G26 R30 R91 G93 T94 E198 G24 R28 R89 G91 T92 E196 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3012 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c B 2.2 BS03 BAU B 1 T94 T95 G96 F162 Q166 R168 E196 M197 I220 P229 T92 T93 G94 F160 Q164 R166 E194 M195 I218 P227 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5011 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c C 2.2 BS01 PO4 C 1 G26 R30 R91 G93 T94 E198 G23 R27 R88 G90 T91 E195 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3022 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c C 2.2 BS02 BAU C 1 T94 T95 G96 F162 Q166 R168 E196 I220 V221 P229 T91 T92 G93 F159 Q163 R165 E193 I217 V218 P226 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5021 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c C 2.2 BS03 BAU D 1 F7 H8 F4 H5 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5031 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c D 2.2 BS01 BAU C 1 F7 H8 F4 H5 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M223 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5021 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQMKQTESHAVKIVVEAARRLL 1u1c D 2.2 BS02 PO4 D 1 G26 R30 R91 G93 T94 E198 G23 R27 R88 G90 T91 E195 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M223 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3032 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQMKQTESHAVKIVVEAARRLL 1u1c D 2.2 BS03 BAU D 1 T94 T95 G96 F162 Q166 R168 E196 I220 T91 T92 G93 F159 Q163 R165 E193 I217 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M223 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5031 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQMKQTESHAVKIVVEAARRLL 1u1c E 2.2 BS01 PO4 E 1 G26 R30 R91 G93 T94 E198 G24 R28 R89 G91 T92 E196 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3042 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c E 2.2 BS02 BAU E 1 T94 T95 G96 F162 Q166 R168 E196 I220 T92 T93 G94 F160 Q164 R166 E194 I218 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5041 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c E 2.2 BS03 BAU F 1 F7 H8 F5 H6 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H6 G24 R28 R46 E78 R89 T92 R166 I218 V219 R221 M232 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5051 KSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c F 2.2 BS01 BAU E 1 F7 H8 F4 H5 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5041 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c F 2.2 BS02 PO4 F 1 G26 R30 R91 G93 T94 E198 G23 R27 R88 G90 T91 E195 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 P12758 15983408 3052 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL 1u1c F 2.2 BS03 BAU F 1 T94 T95 G96 F162 Q166 R168 E196 I220 P229 T91 T92 G93 F159 Q163 R165 E193 I217 P226 H8 G26 R30 R48 E80 R91 T94 R168 I220 V221 R223 M234 H5 G23 R27 R45 E77 R88 T91 R165 I217 V218 R220 M231 2.4.2.3 0003824,0004850,0005524,0005737,0005829,0006218,0006974,0009116,0009164,0009166,0016757,0016763,0030955,0032991,0042802,0044206,0046050,0047847 Ki~4300nM P12758 15983408 5051 SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL