1tg5 A 1.9 BS01 FE2 A 1 H205 H287 E373 H187 H257 E343 1.13.11.27 0003868,0005506,0005737,0006559,0006572,0009072,0016701,0042802,0046872,0051213 P93836 15301540 500 KNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKASEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAESGLNSAVLASNDEMVLLPINEPVHGTKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCYQSGGCGGFGKGNFSELFKSI 1tg5 A 1.9 BS02 645 A 1 L244 P259 H287 F360 F371 E373 F398 G399 K400 N402 F403 L406 L216 P231 H257 F330 F341 E343 F359 G360 K361 N363 F364 L367 1.13.11.27 0003868,0005506,0005737,0006559,0006572,0009072,0016701,0042802,0046872,0051213 ic50=12nM -logKd/Ki=7.92, IC50=12nM P93836 15301540 501 KNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKASEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAESGLNSAVLASNDEMVLLPINEPVHGTKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCYQSGGCGGFGKGNFSELFKSI