1tfz A 1.8 BS01 FE A 1 H205 H287 E373 H184 H252 E338 1.13.11.27 0003868,0005506,0005737,0006559,0006572,0009072,0016701,0042802,0046872,0051213 P93836 15301540 425 NPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFASGLNSAVLASNDEMVLLPINEPVHGKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMQSGGCGGFGKGNFSELFK 1tfz A 1.8 BS02 869 A 1 H205 P259 H287 M314 F360 F398 G399 N402 F403 H184 P227 H252 M279 F325 F354 G355 N358 F359 1.13.11.27 0003868,0005506,0005737,0006559,0006572,0009072,0016701,0042802,0046872,0051213 ic50=7nM -logKd/Ki=8.15, IC50=7nM P93836 15301540 551 NPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFASGLNSAVLASNDEMVLLPINEPVHGKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMQSGGCGGFGKGNFSELFK