1qf5 A 2.0 BS01 PO4 A 1 G12 D13 K16 A39 G40 H41 Q224 G12 D13 K16 A39 G40 H41 Q224 D13 K16 G40 H41 Q224 D13 K16 G40 H41 Q224 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0005829,0006164,0006974,0015949,0016020,0016874,0044208,0046040,0046086,0046872,0097216 P0A7D4 10556888 432 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA 1qf5 A 2.0 BS02 MG A 1 D13 G40 D13 G40 D13 K16 G40 H41 Q224 D13 K16 G40 H41 Q224 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0005829,0006164,0006974,0015949,0016020,0016874,0044208,0046040,0046086,0046872,0097216 P0A7D4 10556888 433 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA 1qf5 A 2.0 BS03 GDP A 1 D13 G15 K16 G17 G40 H41 T42 K331 D333 S414 G416 P417 D13 G15 K16 G17 G40 H41 T42 K331 D333 S414 G416 P417 D13 K16 G40 H41 Q224 D13 K16 G40 H41 Q224 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0005829,0006164,0006974,0015949,0016020,0016874,0044208,0046040,0046086,0046872,0097216 P0A7D4 10556888 434 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA 1qf5 A 2.0 BS04 RPL A 1 D13 N38 G40 G127 T128 T129 Q224 L228 V238 V273 G298 A299 T300 T301 R303 D13 N38 G40 G127 T128 T129 Q224 L228 V238 V273 G298 A299 T300 T301 R303 D13 K16 G40 H41 Q224 D13 K16 G40 H41 Q224 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0005829,0006164,0006974,0015949,0016020,0016874,0044208,0046040,0046086,0046872,0097216 ic50=0.043uM -logKd/Ki=7.37, IC50=0.043uM P0A7D4 10556888 435 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA