1pqc A 2.8 BS01 444 A 1 F271 A275 M312 T316 F329 L345 F349 H435 F45 A49 M86 T90 F103 L119 F123 H209 ? 0003677,0004879,0006629 -logKd/Ki=7.00, IC50=0.1uM IC50=9nM, EC50=170nM, Ki=41nM, Kd=103nM P55055 12819202 1500 LTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWD 1pqc B 2.8 BS01 444 B 1 F268 F271 M312 L313 T316 F329 Y335 L345 F349 I353 H435 L442 W457 F48 F51 M92 L93 T96 F109 Y115 L125 F129 I133 H215 L222 W237 ? 0003677,0004879,0006629 IC50=9nM, EC50=170nM, Ki=41nM, Kd=103nM P55055 12819202 2500 QLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWD 1pqc C 2.8 BS01 444 C 1 F271 L274 A275 M312 L313 T316 I353 H435 W457 F44 L47 A48 M85 L86 T89 I126 H208 W230 ? 0003677,0004879,0006629 IC50=9nM, EC50=170nM, Ki=41nM, Kd=103nM P55055 12819202 3500 LTAAQELMIQQLVAAQLQCNKRSFKVTPWPLQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWD 1pqc D 2.8 BS01 444 D 1 F271 L274 A275 M312 L313 T316 H435 W457 F39 L42 A43 M80 L81 T84 H200 W218 ? 0003677,0004879,0006629 IC50=9nM, EC50=170nM, Ki=41nM, Kd=103nM P55055 12819202 4500 LTAAQELMIQQLVAAQLQCNKRSVTPWSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRKLPPLLSEIWD