1ong A 1.1 BS01 MA4 A 1 V224 P226 V261 I263 I279 A280 A284 V199 P201 V234 I236 I252 A253 A257 S70 K73 S130 E166 K234 A237 S45 K48 S105 E141 K209 A212 3.5.2.6 0008800,0016787,0017001,0030655,0046677 P0AD64 14609325 300 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 1ong A 1.1 BS02 MA4 A 2 L220 I279 L195 I252 S70 K73 S130 E166 K234 A237 S45 K48 S105 E141 K209 A212 3.5.2.6 0008800,0016787,0017001,0030655,0046677 P0AD64 14609325 310 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 1ong A 1.1 BS03 WY4 A 1 S70 Y105 S130 N132 N170 G236 A237 S45 Y80 S105 N107 N145 G211 A212 S70 K73 S130 E166 K234 A237 S45 K48 S105 E141 K209 A212 3.5.2.6 0008800,0016787,0017001,0030655,0046677 -logKd/Ki=8.05, IC50=9nM P0AD64 14609325 400 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR