1o5r A 2.35 BS01 ZN A 1 H15 H17 H214 D295 H12 H14 H211 D292 H15 H17 H214 E217 H238 D295 H12 H14 H211 E214 H235 D292 3.5.4.4 0004000,0005515,0005737,0005764,0005829,0005886,0006154,0007155,0008270,0009117,0009168,0009897,0016787,0019239,0031410,0042110,0043103,0046103,0046872,0046936,0060169,0060205,0070161 P56658 15239652 400 TPAFDKPKVELHVHLDGAIKPETILYYGKRRGIALPADTPEELQNIIGMDKPLTLPDFLAKFDYYMPAIAGCRDAIKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVQAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDTTLYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYR 1o5r A 2.35 BS02 FR9 A 1 H17 D19 F61 L62 F65 M155 D185 T269 D296 H14 D16 F58 L59 F62 M152 D182 T266 D293 H15 H17 H214 E217 H238 D295 H12 H14 H211 E214 H235 D292 3.5.4.4 0004000,0005515,0005737,0005764,0005829,0005886,0006154,0007155,0008270,0009117,0009168,0009897,0016787,0019239,0031410,0042110,0043103,0046103,0046872,0046936,0060169,0060205,0070161 Ki=7.5nM -logKd/Ki=8.12, Ki=7.5nM P56658 15239652 1001 TPAFDKPKVELHVHLDGAIKPETILYYGKRRGIALPADTPEELQNIIGMDKPLTLPDFLAKFDYYMPAIAGCRDAIKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVQAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDTTLYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYR