1nzq H 2.18 BS01 peptide L 0 E23 I24 G25 M26 P28 W29 H119 P120 C122 Y134 K135 R137 N159 M201 K202 R206 W207 E8 I9 G10 M11 P13 W14 H116 P117 C119 Y134 K135 R137 N157 M204 K205 R211 W212 3.4.21.5 0004252,0005509,0006508,0007596 P00734 12781189 1B~ 15 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 1nzq H 2.18 BS02 peptide D 0 Q38 L40 R67 R73 T74 R75 Y76 I82 Q24 L26 R62 R68 T69 R70 Y71 I78 3.4.21.5 0004252,0005509,0006508,0007596 P00734 12781189 55 ~ 65 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 1nzq H 2.18 BS03 162 H 1 H57 Y60A W60D D189 A190 E192 S195 S214 W215 G216 E217 G219 H43 Y47 W50 D192 A193 E195 S198 S219 W220 G221 E222 G223 3.4.21.5 0004252,0005509,0006508,0007596 ic50=11nM -logKd/Ki=7.96, IC50=11nM P00734 12781189 248 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF