1mnc A 2.1 BS01 ZN A 1 H218 H222 H228 H113 H117 H123 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.34 0004222,0006508,0008237,0008270,0031012 P22894 7656015 281 GPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTGISQGEADINIAFYQRDHGDGSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG 1mnc A 2.1 BS02 ZN A 2 H168 D170 H183 H196 H63 D65 H78 H91 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.34 0004222,0006508,0008237,0008270,0031012 P22894 7656015 282 GPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTGISQGEADINIAFYQRDHGDGSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG 1mnc A 2.1 BS03 CA A 1 D175 G176 N178 I180 D198 E201 D70 G71 N73 I75 D93 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.34 0004222,0006508,0008237,0008270,0031012 P22894 7656015 283 GPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTGISQGEADINIAFYQRDHGDGSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG 1mnc A 2.1 BS04 PLH A 1 G179 I180 L181 A182 H218 E219 H222 H228 P238 N239 Y240 G74 I75 L76 A77 H113 E114 H117 H123 P133 N134 Y135 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.34 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=10.34, IC50=0.046nM P22894 7656015 280 GPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTGISQGEADINIAFYQRDHGDGSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG