1lt6 D 2.2 BS01 GAA D 1 Y12 E51 H57 Q61 W88 N90 K91 Y12 E51 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 -logKd/Ki=3.30, IC50=0.5mM P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 E 2.2 BS01 GAA E 1 E51 H57 Q61 W88 N90 K91 E51 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 -logKd/Ki=3.30, IC50=0.5mM P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 F 2.2 BS01 GAA F 1 Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 G 2.2 BS01 GAA G 1 R13 E51 Q56 H57 Q61 W88 N90 K91 R13 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 H 2.2 BS01 GAA H 1 Y12 E51 Q56 H57 W88 N90 K91 Y12 E51 Q56 H57 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 L 2.2 BS01 GAA L 1 E51 Q56 H57 Q61 W88 N90 K91 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 M 2.2 BS01 GAA M 1 Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 N 2.2 BS01 GAA N 1 Y12 E51 H57 Q61 W88 N90 K91 Y12 E51 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 O 2.2 BS01 GAA O 1 Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN 1lt6 P 2.2 BS01 GAA P 1 E51 Q56 H57 Q61 W88 N90 K91 E51 Q56 H57 Q61 W88 N90 K91 ? 0005576,0031640,0035821,0090729 P32890 9384564 104 APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN